A Way For Accelerating The DNA Sequence Reconstruction Problem By CUDA

نویسندگان

  • Yukun Zhong
  • Zhiwei He
  • Xianhong Wang
  • Xiongbin Cao
چکیده

Traditionally, we usually utilize the method of shotgun to cut a DNA sequence into pieces and we have to reconstruct the original DNA sequence from the pieces, those are widely used method for DNA assembly. Emerging DNA sequence technologies open up more opportunities for molecular biology. This paper introduce a new method to improve the efficiency of reconstructing DNA sequence using suffix array based on CUDA programming model. The experimental result show the construction of suffix array using GPU is an more efficient approach on Intel(R) Core(TM) i3-3110K quad-core and NVIDIA GeForce 610M GPU, and study show the performance of our method is more than 20 times than that of CPU serial implementation. We believe our method give a cost-efficient solution to the bioinformatics community. keywords-CUDA, DNA Sequence assembly, GPU, shotgun method , Supersring, Suffix Array, Radix Sort

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Accelerating high-order WENO schemes using two heterogeneous GPUs

A double-GPU code is developed to accelerate WENO schemes. The test problem is a compressible viscous flow. The convective terms are discretized using third- to ninth-order WENO schemes and the viscous terms are discretized by the standard fourth-order central scheme. The code written in CUDA programming language is developed by modifying a single-GPU code. The OpenMP library is used for parall...

متن کامل

Parallelizing Assignment Problem with DNA Strands

Background:Many problems of combinatorial optimization, which are solvable only in exponential time, are known to be Non-Deterministic Polynomial hard (NP-hard). With the advent of parallel machines, new opportunities have been emerged to develop the effective solutions for NP-hard problems. However, solving these problems in polynomial time needs massive parallel machines and ...

متن کامل

A MODEL FOR THE BASIC HELIX- LOOPHELIX MOTIF AND ITS SEQUENCE SPECIFIC RECOGNITION OF DNA

A three dimensional model of the basic Helix-Loop-Helix motif and its sequence specific recognition of DNA is described. The basic-helix I is modeled as a continuous ?-helix because no ?-helix breaking residue is found between the basic region and the first helix. When the basic region of the two peptide monomers are aligned in the successive major groove of the cognate DNA, the hydrophobi...

متن کامل

Accelerating GOR Algorithm Using CUDA

Protein secondary structure prediction is very important for its molecular structure. GOR algorithm is one of the most successful computational methods and has been widely used as an efficient analysis tool to predict secondary structure from protein sequence. However, the running time is unbearable with sharp growth in protein database. Fortunately, CUDA (Compute Unified Device Architecture) p...

متن کامل

gpALIGNER: A Fast Algorithm for Global Pairwise Alignment of DNA Sequences

Bioinformatics, through the sequencing of the full genomes for many species, is increasingly relying on efficient global alignment tools exhibiting both high sensitivity and specificity. Many computational algorithms have been applied for solving the sequence alignment problem. Dynamic programming, statistical methods, approximation and heuristic algorithms are the most common methods appli...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • CoRR

دوره abs/1404.3456  شماره 

صفحات  -

تاریخ انتشار 2014